Destroy All Humans! is a 2005 action-adventure video game developed by Pandemic Studios and published by THQ for PlayStation 2, Xbox, and mobile phones. The game is the first installment in the Destroy All Humans! franchise, and is set in 1959 in the United States, and parodies the lifestyles, pop culture, and political attitudes of this time period. The player controls Cryptosporidium 137 (a reference to the protozoan parasite Cryptosporidium), a member of a fictional exaggerated alien race called "Furons", and is a Furon spy hitman invading Earth to harvest DNA from humans to continue the cloning process of his species. Destroy All Humans! received generally positive reviews from critics. The original was ported to PlayStation 4 in 2016 alongside its sequel. A full remake of the game was released on July 28, 2020.