Extermination is a 2001 survival horror game developed by Deep Space and published by Sony Computer Entertainment for the PlayStation 2. It was used as a showcase for the system at trade shows before its release. The game was considered the first survival horror release for the PS2 and generated some hype amongst critics, but it received mixed reviews.

There are significant differences between the European and North American versions of the game including a redesign of the main protagonist, and entirely rerecorded dialogue using different voice actors. Former members of the development team joined Access Games.